HCID 20393551, compound → HCID 20393559, compound

HRID 1862928Notes

Reaction equation

HRID 1862928 reaction equation
[OH:1][CH:2]([CH2:39][N:40]([CH2:51][CH2:52][OH:53])[CH:41]1[CH2:46][C:45]([CH3:48])([CH3:47])[NH:44][C:43]([CH3:50])([CH3:49])[CH2:42]1)[CH2:3][O:4][C:5]1[CH:10]=[CH:9][C:8]([C:11]([C:14]2[CH:19]=[CH:18][C:17]([O:20][CH2:21][CH:22]([OH:38])[CH2:23][N:24]([CH:28]3[CH2:33][C:32]([CH3:35])([CH3:34])[NH:31][C:30]([CH3:37])([CH3:36])[CH2:29]3)[CH2:25][CH2:26][OH:27])=[CH:16][CH:15]=2)([CH3:13])[CH3:12])=[CH:7][CH:6]=1>C(OC(=O)C)(=O)C>[C:17]([O:38][CH:22]([CH2:23][N:24]([CH2:25][CH2:26][O:27][C:2](=[O:1])[CH3:3])[CH:28]1[CH2:33][C:32]([CH3:35])([CH3:34])[N:31]([C:5](=[O:4])[CH3:6])[C:30]([CH3:37])([CH3:36])[CH2:29]1)[CH2:21][O:20][C:17]1[CH:18]=[CH:19][C:14]([C:11]([C:8]2[CH:7]=[CH:6][C:5]([O:4][CH2:3][CH:2]([O:1][C:26](=[O:27])[CH3:25])[CH2:39][N:40]([CH:41]3[CH2:42][C:43]([CH3:50])([CH3:49])[N:44]([C:22](=[O:38])[CH3:21])[C:45]([CH3:48])([CH3:47])[CH2:46]3)[CH2:51][CH2:52][O:53][C:52](=[O:53])[CH3:51])=[CH:10][CH:9]=2)([CH3:13])[CH3:12])=[CH:15][CH:16]=1)(=[O:20])[CH3:16]

Participants

3

Reactant 1

HCID 20393551HCID 20393551, compound

Product 1

HCID 20393559HCID 20393559, compound

Reagents, catalysts & solvents 1

HCID 7918Acetic AnhydrideSolvent

Procedure

A mixture of 200 ml of acetic anhydride and 7.4 g of 2,2-bis[4-{2-hydroxy-3-[N-(2-hydroxyethyl)-N-(2,2,6,6-tetramethyl-4-piperidyl)amino]propoxy}phenyl]propane, obtained as described in Example 17, was reacted in a manner similar to that described in Example 13, giving the desired compound in the form of a pale yellow, very viscous product. The compound had an Rf value of 0.61 on thin layer chromatography on silica gel developed with a 20:4:2:1 by volume mixture of ethyl acetate, benzene, ethanol and triethylamine.

Workup

  1. customobtained
  2. customwas reacted in a manner similar to

Sources & evidence

ORD record
ord-ce214fe5f529459b851d3bed37f1cc62
Source dataset
uspto-grants-1979_09
Patent number
US04166813

Reaction notes

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