Nitric Acid → HCID 12393933, compound

HRID 1862984Notes

Reaction equation

HRID 1862984 reaction equation
S(=O)(=O)(O)O.[N+:6]([O-:9])(O)=[O:7].[CH3:10][O:11][C:12]1[CH:16]=[CH:15][S:14][N:13]=1>>[N+:6]([C:16]1[C:12]([O:11][CH3:10])=[N:13][S:14][CH:15]=1)([O-:9])=[O:7]

Participants

4

Reactant 3

HCID 944Nitric AcidHCID 1118Sulfuric AcidHCID 123939283-Methoxy-1,2-thiazole

Product 1

HCID 12393933HCID 12393933, compound

Procedure

To a solution of 10 ml. of concentrated sulfuric acid and 2 g. (0.022 mole) of 70% nitric acid was added over several minutes 2.3 g. (0.02 mole) of 3-methoxyisothiazole. The temperature rose to 40° C. and was controlled at that point by cooling. After stirring for 5 hours the reaction solution was poured into 30 ml. of ice-water to precipitate 0.5 g. (16%) of 4-nitro-3-methoxyisothiazole as a white solid, m.p. 118°-122° C.

Workup

  1. customrose to 40° C.
  2. temperatureby cooling
  3. additionwas poured into 30 ml
  4. customof ice-water to precipitate 0.5 g

Sources & evidence

ORD record
ord-53f46df065b544ceb5a838b116e4fe60
Source dataset
uspto-grants-1979_09
Patent number
US04167575

Reaction notes

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