Benzene, 1-chloro-3-isocyanato- → HCID 54029564, compound

HRID 1863028Notes

Reaction equation

HRID 1863028 reaction equation
[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([NH:12][C:13]3[CH:26]=[CH:25][C:16]([C:17]([N:19]4[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]4)=[O:18])=[CH:15][CH:14]=3)=[CH:7][CH:8]=[N:9]2)=[CH:4][CH:3]=1.[Cl:27][C:28]1[CH:29]=[C:30]([N:34]=[C:35]=[O:36])[CH:31]=[CH:32][CH:33]=1>>[Cl:27][C:28]1[CH:29]=[C:30]([NH:34][C:35]([N:22]2[CH2:21][CH2:20][N:19]([C:17](=[O:18])[C:16]3[CH:25]=[CH:26][C:13]([NH:12][C:6]4[C:5]5[C:10](=[CH:11][C:2]([Cl:1])=[CH:3][CH:4]=5)[N:9]=[CH:8][CH:7]=4)=[CH:14][CH:15]=3)[CH2:24][CH2:23]2)=[O:36])[CH:31]=[CH:32][CH:33]=1

Participants

3

Reactant 2

HCID 17968Benzene, 1-chloro-3-isocyanato-HCID 20392885HCID 20392885, compound

Product 1

HCID 54029564HCID 54029564, compound

Procedure

In the manner given in Example 23, 4-[4-[[7-(chloro)-4-quinolinyl]amino]benzoyl]piperazine is reacted with m-chlorophenyl isocyanate to give 1-[[(3-chlorophenyl)amino]carbonyl]-4-[4-[[(7-chloro)-4-quinolinyl]amino]benzoyl]piperazine.

Sources & evidence

ORD record
ord-5fb9c84bf14241879af3318bbfe781fa
Source dataset
uspto-grants-1979_09
Patent number
US04167567

Reaction notes

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