HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropylamine → N-(1-Methylethyl)-4-nitro-2-(trifluoromethyl)benzenamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropylamine | HCID 6363 | — |
| Reactant | 2-Chloro-5-nitrobenzotrifluoride | HCID 61213 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | N-(1-Methylethyl)-4-nitro-2-(trifluoromethyl)benzenamine | HCID 20392080 | 100.2% |
Reaction Steps
To a solution of 45 g of 3-(trifluoromethyl)-4-chloronitrobenzene in 150 ml of DMSO was added 13 g of isopropylamine. The mixture was heated at 80°-90° C. for two hours, poured over ice water, acidified and filtered. The filter cake was dried to yield 49.6 g of product; m.p. 35°-36° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04168153 |
| Source dataset | uspto-grants-1979_09 |
| ORD ID | ord-53e8b43e3737455abc120b80728ee359 |
| Source note | uspto-grants-1979_09 |