2,3,4,5,6-Pentafluorobenzophenone → HCID 22481417, compound

HRID 1863144Notes

Reaction equation

HRID 1863144 reaction equation
[F:1][C:2]1[C:7]([C:8]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[O:9])=[C:6]([F:16])[C:5]([F:17])=[C:4]([F:18])[C:3]=1[F:19]>C1C=CC=CC=1.C(O)(C)C>[F:1][C:2]1[C:7]([C:8]([C:8]([C:7]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[OH:9])([OH:9])[C:10]2[C:15]([F:1])=[C:14]([F:16])[C:13]([F:17])=[C:12]([F:18])[C:11]=2[F:19])=[C:6]([F:16])[C:5]([F:17])=[C:4]([F:18])[C:3]=1[F:19]

Participants

3

Reactant 1

HCID 737552,3,4,5,6-Pentafluorobenzophenone

Product 1

HCID 22481417HCID 22481417, compound

Reagents, catalysts & solvents 1

HCID 20154085HCID 20154085, compoundSolvent

Procedure

Pentafluorobenzophenone (10.4 g) was dissolved in 250 ml of benzene/isopropanol (3.5:1). The solution was purged with nitrogen and irradiated for 6 hours with a Hanovia 450-watt Hg-arc lamp. The solvent was removed using a vacuum evaporator at a temperature less than 40° C. The crystallized product was washed twice with 25 ml of n-pentane. The slurry was centrifuged and n-pentane was decanted. The product was spread on a watch glass and air dried. Recovery of 2,3,4,5,6,2',3',4',5',6'-decafluorobenzopinacol was 9.1 g or 87.5%.

Workup

  1. customThe solution was purged with nitrogen
  2. customirradiated for 6 hours with a Hanovia 450-watt Hg-arc lamp
  3. customThe solvent was removed
  4. customa vacuum evaporator at a temperature less than 40° C
  5. washThe crystallized product was washed twice with 25 ml of n-pentane
  6. customn-pentane was decanted
  7. customdried

Sources & evidence

ORD record
ord-8fa33a14a54c428d861f2ec3680721d2
Source dataset
uspto-grants-1979_09
Patent number
US04168218

Reaction notes

Loading…