Sodium Hydroxide → HCID 131711630, compound

HRID 1863197Notes

Reaction equation

HRID 1863197 reaction equation
[OH:1][P:2]([CH2:11][C:12]([N:14]1[CH2:21][CH2:20][CH2:19][C@H:15]1[C:16]([OH:18])=[O:17])=[O:13])([CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=[O:3].[OH-].[Na+:23]>O>[Na+:23].[Na+:23].[OH:3][P:2]([CH2:11][C:12]([N:14]1[CH2:21][CH2:20][CH2:19][C@H:15]1[C:16]([O-:18])=[O:17])=[O:13])([CH2:4][C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][CH:10]=1)=[O:1].[OH:3][P:2]([CH2:11][C:12]([N:14]1[CH2:21][CH2:20][CH2:19][C@H:15]1[C:16]([O-:18])=[O:17])=[O:13])([CH2:4][C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][CH:10]=1)=[O:1]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 54119754HCID 54119754, compound

Product 1

HCID 131711630HCID 131711630, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

1-[[Hydroxy(phenylmethyl)phosphinyl]acetyl]-L-proline is dissolved in water and treated with two molar equivalents of aqueous sodium hydroxide. The resulting solution is lyophilized to give the product, 1-[[hydroxy(phenylmethyl) phosphinyl]acetyl]-L-proline disodium salt.

Sources & evidence

ORD record
ord-c87e90280fcd492d8818e7a3909c2c78
Source dataset
uspto-grants-1979_09
Patent number
US04168267

Reaction notes

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