Dimethylcarbamoyl Chloride → Carbamic acid, dimethyl-, 2,6-dimethyl-4-pyridinyl ester

Participants

Reaction Conditions

Reaction Steps

30,8 g (0,25 mole) of 2,6-dimethyl-4-hydroxypyridine were suspended in 500 ml of acetonitrile, 69 g (0,5 mole) of potassium carbonate were added and the mixture was heated to reflux temperature for 2 hours. Subsequently 47 g (0,44 mole) of dimethylcarbamic acid chloride were added at an interior temperature of approximately 60°-70° C. and the mixture was maintained for two hours at about 80° C.

Provenance & Evidence