Sodium Carbonate → 3-Nitro-4-cyclohexylphenylglyoxylic acid

HRID 1863230Notes

Reaction equation

HRID 1863230 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([C:16](=[O:20])[C:17]([O-:19])=[O:18])[CH:7]=[CH:8][C:9]=1[CH:10]1[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]1)([O-:3])=[O:2].C(=O)([O-])[O-].[Na+].[Na+]>>[N+:1]([C:4]1[CH:5]=[C:6]([C:16](=[O:20])[C:17]([OH:19])=[O:18])[CH:7]=[CH:8][C:9]=1[CH:10]1[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]1)([O-:3])=[O:2]

Participants

3

Reactant 2

HCID 10340Sodium CarbonateHCID 205151903-Nitro-4-cyclohexylphenylglyoxylate

Product 1

HCID 205151913-Nitro-4-cyclohexylphenylglyoxylic acid

Procedure

A mixture of 0.66 moles of 3-nitro-4-cyclohexylphenylglyoxylate is stirred in 1.5 l. of boiling 10% sodium carbonate solution for 16 hours. The mixture is slowly filtered through charcoal into 1.1 l. of ice-cold 3-N-hydrochloric acid. The precipitate of crude material is collected on a filter, the recrystallized from benzene to give 3-nitro-4-cyclohexylphenylglyoxylic acid.

Workup

  1. customfor 16 hours
  2. filtrationThe mixture is slowly filtered through charcoal into 1.1 l
  3. customThe precipitate of crude material is collected on a filter
  4. customthe recrystallized from benzene

Sources & evidence

ORD record
ord-6ddc5bf9d9204c759db93f12ea2e77e3
Source dataset
uspto-grants-1979_09
Patent number
US04168320

Reaction notes

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