alpha,beta-Dibromopropionate → 3-Chloro-4-cyclohexylpropiolic acid

HRID 1863234Notes

Reaction equation

HRID 1863234 reaction equation
Br[CH:2]([CH:6](Br)[CH:7]1[CH2:12][CH2:11][CH2:10][CH2:9][CH:8]1[Cl:13])[C:3]([O-:5])=[O:4].BrC(CBr)C([O-])=O>>[Cl:13][CH:8]1[CH:7]([C:6]#[C:2][C:3]([OH:5])=[O:4])[CH2:12][CH2:11][CH2:10][CH2:9]1

Participants

3

Reactant 2

HCID 14535401alpha,beta-DibromopropionateHCID 131710453alpha,beta-Dibromo-beta-(3-chloro-4cyclohexyl)propionate

Product 1

HCID 705420153-Chloro-4-cyclohexylpropiolic acid

Procedure

When α,β-dibromo-β-(3-chloro-4-cyclohexyl)propionate in the above example is replaced by the α,β-dibromopropionate of Example 26, then the corresponding propiolic acid is prepared.

Sources & evidence

ORD record
ord-ce9db0c73e944c569ff489e869ddebf0
Source dataset
uspto-grants-1979_09
Patent number
US04168320

Reaction notes

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