Acetic Anhydride → HCID 12803438, compound

HRID 1863241Notes

Reaction equation

HRID 1863241 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH:9]=[C:8]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[NH:7][C:6]1=[O:16].[C:17](OC(=O)C)(=[O:19])[CH3:18]>>[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH:9]=[C:8]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[N:7]([C:17](=[O:19])[CH3:18])[C:6]1=[O:16]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 12803422HCID 12803422, compound

Product 1

HCID 12803438HCID 12803438, compound

Procedure

Approximately 21.8 g of 1-(2-methoxyethyl)-4-phenyl-4-imidazolin-2-one and 120 ml. of acetic anhydride is refluxed together for four hours. The acetic anhydride is distilled out at reduced pressure. The residual semisolid is recrystallized from ethyl acetate to yield the title compound as a white solid; m.p. 81°-82° C.

Workup

  1. distillationThe acetic anhydride is distilled out at reduced pressure
  2. customThe residual semisolid is recrystallized from ethyl acetate

Sources & evidence

ORD record
ord-44c75b46c6de42d5a47eb47c3edc5a1a
Source dataset
uspto-grants-1979_09
Patent number
US04168381

Reaction notes

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