Ethyl [p-(p-nitrophenoxy)phenyl]acetate → HCID 20392571, compound

HRID 1863269Notes

Reaction equation

HRID 1863269 reaction equation
[CH2:1]([O:3][C:4](=[O:22])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][C:13]2[CH:18]=[CH:17][C:16]([N+:19]([O-])=O)=[CH:15][CH:14]=2)=[CH:8][CH:7]=1)[CH3:2]>C(O)C.[Pt]=O>[CH2:1]([O:3][C:4](=[O:22])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][C:13]2[CH:14]=[CH:15][C:16]([NH2:19])=[CH:17][CH:18]=2)=[CH:8][CH:7]=1)[CH3:2]

Participants

4

Reactant 1

HCID 20392616Ethyl [p-(p-nitrophenoxy)phenyl]acetate

Product 1

HCID 20392571HCID 20392571, compound

Reagents, catalysts & solvents 2

HCID 82844Platinum oxide (PtO)CatalystHCID 702EthanolSolvent

Procedure

A mixture of 7.5 g of ethyl[p-(p-nitrophenoxy)phenyl]acetate and 200 mg of platinum oxide in 200 ml of ethanol is shaken under 45 lbs of hydrogen for one hour and then filtered through diatomaceous earth which is washed with 20 ml of ethanol. The combined filtrate and washings are concentrated to a yellow oil. Bulb-to-bulb distillation affords a pale yellow opaque oil, b.p. 176° @ 0.1 mm.

Workup

  1. filtrationfiltered through diatomaceous earth which
  2. washis washed with 20 ml of ethanol
  3. concentrationThe combined filtrate and washings are concentrated to a yellow oil
  4. distillationBulb-to-bulb distillation
  5. customaffords a pale yellow opaque oil, b.p. 176°

Sources & evidence

ORD record
ord-168e5bcf184d449fadb81bf68385e6cc
Source dataset
uspto-grants-1979_09
Patent number
US04168385

Reaction notes

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