反应详情

To a solution of 4.49 g of sodium metaperiodate in 80 ml of water is added a solution of 5.57 g of [p-(p-chlorophenylthio)phenyl]acetic acid in 75 ml of 1.75% NaOH. A white solid precipitates immediately. After stirring overnight the mixture is filtered and the filtrate is acidified with concentrated HCl to give a white solid. This product, which contains some starting material, is reworked, as above, to yield the pure product. Recrystallization from chloroform-hexane affords white crystals, mp 139°-141° C. and 144°-148.5° C.

1. customA white solid precipitates immediately
2. filtrationis filtered
3. customto give a white solid
4. customas above, to yield the pure product
5. customRecrystallization from chloroform-hexane
6. customaffords white crystals, mp 139°-141° C. and 144°-148.5° C.