Phenol → HCID 20392617, compound

HRID 1863288Notes

Reaction equation

HRID 1863288 reaction equation
Br[CH:2]([C:7]1[CH:12]=[CH:11][C:10]([I:13])=[CH:9][CH:8]=1)[C:3]([O:5][CH3:6])=[O:4].[C:14]1([OH:20])[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>CO>[O:20]([CH:2]([C:7]1[CH:12]=[CH:11][C:10]([I:13])=[CH:9][CH:8]=1)[C:3]([O:5][CH3:6])=[O:4])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

Participants

4

Reactant 2

HCID 996PhenolHCID 20392584Methyl α-bromo-4-iodobenzeneacetate

Product 1

HCID 20392617HCID 20392617, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In a similar manner as in Example 29, 14.2 g of methyl α-bromo-α-(p-iodophenyl)acetate is reacted with 4.70 g of phenol in methanol to yield a white to light pink solid, mp 68°-71° C. Recrystallization from petroleum ether yields the product as white crystals, mp 72.5°-74° C.

Workup

  1. customto yield a white
  2. customRecrystallization from petroleum ether

Sources & evidence

ORD record
ord-df026f8743d84542a6656d50de9f8cba
Source dataset
uspto-grants-1979_09
Patent number
US04168385

Reaction notes

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