Potassium Carbonate → HCID 20392596, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 2.21 g of p-fluorobenzonitrile, 2.16 g of ethyl p-hydroxyphenylacetate and 2.07 g of K2CO3 in 20 ml of N,N-dimethylacetamide is stirred and heated at 155° C. for 18 hours. The mixture is chilled and poured into 40 ml of cold saturated NaHCO3 solution. The mixture is extracted with ether and the extracts washed with cold 2 N NaOH and saline. The extracts are dried (MgSO4) and concentrated under vacuum to give the product as a yellow oil.

Provenance & Evidence