HCID 12531881, compound → HCID 20392639, compound

HRID 1863330Notes

Reaction equation

HRID 1863330 reaction equation
[C:1]([C:5]1[CH:32]=[CH:31][C:8]([O:9][CH:10]([C:15]2[CH:20]=[CH:19][C:18]([O:21][C:22]3[CH:27]=[CH:26][C:25]([N+:28]([O-])=O)=[CH:24][CH:23]=3)=[CH:17][CH:16]=2)[C:11]([O:13][CH3:14])=[O:12])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2]>CO.[Pd]>[C:1]([C:5]1[CH:32]=[CH:31][C:8]([O:9][CH:10]([C:15]2[CH:20]=[CH:19][C:18]([O:21][C:22]3[CH:23]=[CH:24][C:25]([NH2:28])=[CH:26][CH:27]=3)=[CH:17][CH:16]=2)[C:11]([O:13][CH3:14])=[O:12])=[CH:7][CH:6]=1)([CH3:4])([CH3:2])[CH3:3]

Participants

4

Reactant 1

HCID 12531881HCID 12531881, compound

Product 1

HCID 20392639HCID 20392639, compoundYield 103.5%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

To a suspension of 2.18 g of methyl α-(p-tert-butylphenoxy)-α-[p-(p-nitrophenoxy)phenyl]acetate in 50 ml of methanol was added 160 mg of 10% palladium on carbon and the mixture hydrogenated with shaking. The mixture was filtered and the filtrate concentrated under vacuum to give 2.1 g of the product as a gum.

Workup

  1. filtrationThe mixture was filtered
  2. concentrationthe filtrate concentrated under vacuum

Sources & evidence

ORD record
ord-4733f023dcf84eb59749469da4c404b6
Source dataset
uspto-grants-1979_09
Patent number
US04168385

Reaction notes

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