HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Chlorophenyl)acetic acid → 4-Chlorophenylacetyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Chlorophenyl)acetic acid | HCID 15880 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Product | 4-Chlorophenylacetyl chloride | HCID 90692 | 71% |
Reaction Steps
The requisite p-chlorophenylacetyl chloride was prepared in the following manner. p-Chlorophenylacetic acid (15 g.; 0.088 mole) and thionyl chloride (31.5 g.; 0.0264 mole) were heated at reflux for 2 hours. Excess thionyl chloride was removed in vacuo to afford the acid chloride which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04168315 |
| Source dataset | uspto-grants-1979_09 |
| ORD ID | ord-46232563a6bb491eb09d98eb48143d0f |
| Source note | uspto-grants-1979_09 |