HuagongsheHuagongshe Chemistry Print Report · For research reference only
Salicylamide → 2-Propoxybenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Salicylamide | HCID 5147 | — |
| Reactant | 1-Iodopropane | HCID 33643 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Propoxybenzamide | HCID 43051 | — |
Reaction Steps
A 130 gm. portion of salicylamide in 500 ml. of ethanol is reacted with 52.4 gm. of sodium methoxide and 164.9 gm. of 1-iodopropane by heating at reflux. The mixture is cooled, precipitated in 1500 ml. of water and the solid is recrystallized from hot ethanol giving o-propoxybenzamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04168964 |
| Source dataset | uspto-grants-1979_09 |
| ORD ID | ord-27db14c2a4d14eb2a8bfda7d9a109dd5 |
| Source note | uspto-grants-1979_09 |