Hydrazinecarboxylic acid, ethyl ester → HCID 178473579, compound

HRID 1863386Notes

Reaction equation

HRID 1863386 reaction equation
[CH2:1]([C:8]1[NH:9][CH:10]=[C:11]([CH:13]=O)[N:12]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:15]([O:19][CH2:20][CH3:21])(=[O:18])[NH:16][NH2:17]>C(O)(=O)C.C(O)C>[CH2:20]([O:19][C:15](=[O:18])[NH:16][N:17]=[CH:13][C:11]1[N:12]=[C:8]([CH2:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[NH:9][CH:10]=1)[CH3:21]

Participants

5

Reactant 2

HCID 20064Hydrazinecarboxylic acid, ethyl esterHCID 178519865HCID 178519865, compound

Product 1

HCID 178473579HCID 178473579, compound

Reagents, catalysts & solvents 2

HCID 176Acetic AcidCatalystHCID 702EthanolSolvent

Procedure

To a 37.2 gm. portion of 2-benzyl-4-imidazolecarboxaldehyde in 200 ml. of ethanol is added 20.8 gm. of ethyl carbazate and a few drops of concentrated acetic acid. The mixture is reacted as described in Example 32 giving the desired product m.p. 184°-185° C.

Workup

  1. customThe mixture is reacted

Sources & evidence

ORD record
ord-8772ae807675419480d9a265a28c6182
Source dataset
uspto-grants-1979_09
Patent number
US04168964

Reaction notes

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