[5-Methyl-2-(3-methylphenyl)-1H-imidazol-4-yl]methanol → 4-Methyl-2-(3-methylphenyl)-1H-imidazole-5-carboxaldehyde

Participants

Reaction Steps

A mixture of 5-methyl-2-m-tolyl-4-imidazolemethanol (13.0 gm., 0.064 mole), activated manganese dioxide (65 gm.) and methylene chloride (200 ml.) is stirred at room temperature for 20 hours. The reaction mixture is then filtered, the solvent removed in vacuo to afford 9.1 gm. (0.045 mole) of peach-colored solid.

Provenance & Evidence