HCID 136486663, compound → HCID 20291380, compound

Participants

Reaction Steps

3-[1-(5-Iodo-2-phenyl-4-imidazolyl)ethylidene]-carbazic acid methyl ester (1.01 gm., 0.0027 mole) is dissolved in a mixture of o-dichlorobenzene (150 ml.) and methanol (15 ml.). The solution is heated to the boiling point and boiled for 20 minutes allowing solvent to distill off partially. The reaction mixture is chromatographed over a silica gel column and eluted with a hexane-ethyl acetate (2:1) mixture to yield the title product (0.63 gm., 0.0019 mole). Recrystallization from ethyl acetate-hexane yields the product as yellow needles, m.p. 176°-189° C.

Provenance & Evidence