Lithium Chloride → HCID 20391996, compound

Participants

Reaction Steps

166 mg (0.33 mmol) of 3-methoxycarbonyl-3-(6-methoxycarbonylhexyl)-4-(1-phenylthio-trans-2-octenyl)-oxolane-2-one was dissolved in 4 ml of hexamethylphosphoric triamide in an argon atmosphere followed by stirring. 70 mg (1.65 mmol) of lithium chloride was then added to the solution and the mixture was stirred at a temperature of 100° C. for 5 hours. The resulting mixture was then worked up in the same manner as described in Example 5 to obtain 61 mg (41% yield) of 3-(6-methoxycarbonylhexyl)-4-(1-phenylthio-trans-2-octenyl)oxolane-2-one.

Provenance & Evidence