Hydrochloric Acid → HCID 86614848, compound

Participants

Reaction Steps

The {(1R)-1-(2,4,5-trifluorobenzyl)-2-[9-(trifluoromethyl)-5,6-dihydrobis[1,2,4]triazolo[1,5-a:3′,4′-c]pyrazin-3-yl]ethyl}amine (free base) from Step A was treated an excess of 4M HCl in anhydrous dioxane, and the mixture was stirred at room temperature for 1 h. The residue obtained upon concentration of the reaction mixture was washed with ether and dried to afford the title compound as a white solid. LC-MS 418 (M+1).

Provenance & Evidence