HCID 57973790, compound → HCID 91285248, compound

Participants

Reaction Steps

A solution of 139 mg (0.4 mmol) of tert-butyl[(1R)-3-hydrazino-3-oxo-1-(2,4,5-trifluorobenzyl)propyl]carbamate (Intermediate 4) and 72.9 mg (0.4 mmol) of 2-methyl-5-(methylthio)-7,8-dihydro[1,2,4]triazolo[1,5-c]pyrimidine (Intermediate 30) in 5 mL of 1-butanol was stirred at reflux for 76 h. The cooled solution was concentrated, and the residue containing the title compound was used directly in the next step. LC-MS 482 (M+1).

Provenance & Evidence