N-Iodosuccinimide → HCID 131727795, compound

HRID 1864017Notes

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C@H:8]2[C@@H:17]([C:18]3[CH:23]=[CH:22][C:21]([Cl:24])=[CH:20][CH:19]=3)[N:11]3[C:12](=[O:16])[CH:13]=[CH:14][CH:15]=[C:10]3[N:9]2[S:25]([C:28]2[CH:29]=[C:30]([CH:33]=[CH:34][CH:35]=2)[C:31]#[N:32])(=[O:27])=[O:26])=[CH:4][CH:3]=1.C1C(=O)N([I:43])C(=O)C1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C@H:8]2[C@@H:17]([C:18]3[CH:19]=[CH:20][C:21]([Cl:24])=[CH:22][CH:23]=3)[N:11]3[C:12](=[O:16])[C:13]([I:43])=[CH:14][CH:15]=[C:10]3[N:9]2[S:25]([C:28]2[CH:29]=[C:30]([CH:33]=[CH:34][CH:35]=2)[C:31]#[N:32])(=[O:27])=[O:26])=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 120273N-Iodosuccinimide

HCID 57973962HCID 57973962, compound

Product 1

HCID 131727795HCID 131727795, compound

Procedure

The titled compound was prepared according to general method B by reaction of rac-3-[cis-2,3-Bis-(4-chloro-phenyl)-5-oxo-2,3-dihydro-5H-imidazo[1,2-a]pyridine-1-sulfonyl]-benzonitrile with NIS.

Sources & evidence

ORD record: ord-4305137dc2a24a5282b86e2f97dd7c64
Source dataset: uspto-grants-2009_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07625895B2

Reaction notes

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