N-Iodosuccinimide → HCID 131727796, compound

HRID 1864018Notes

Reaction equation

[CH3:1][O:2][C:3](=[O:37])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([S:10]([N:13]2[C:17]3=[CH:18][CH:19]=[CH:20][C:21](=[O:22])[N:16]3[C@H:15]([C:23]3[CH:28]=[CH:27][C:26]([Cl:29])=[CH:25][CH:24]=3)[C@@H:14]2[C:30]2[CH:35]=[CH:34][C:33]([Cl:36])=[CH:32][CH:31]=2)(=[O:12])=[O:11])[CH:5]=1.C1C(=O)N([I:45])C(=O)C1>>[CH3:1][O:2][C:3](=[O:37])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([S:10]([N:13]2[C:17]3=[CH:18][CH:19]=[C:20]([I:45])[C:21](=[O:22])[N:16]3[C@H:15]([C:23]3[CH:28]=[CH:27][C:26]([Cl:29])=[CH:25][CH:24]=3)[C@@H:14]2[C:30]2[CH:31]=[CH:32][C:33]([Cl:36])=[CH:34][CH:35]=2)(=[O:11])=[O:12])[CH:5]=1

Participants

Reactant 2

HCID 120273N-Iodosuccinimide

HCID 131727797HCID 131727797, compound

Product 1

HCID 131727796HCID 131727796, compound

Procedure

The titled compound was prepared according to general method B by reaction of rac-3-[cis-2,3-bis-(4-chloro-phenyl)-5-oxo-2,3-dihydro-5H-imidazo[1,2-a]pyridine-1-sulfonyl]-benzoic acid methyl ester with NIS.

Sources & evidence

ORD record: ord-14bcbac66f8d4fc0a28453b33e394368
Source dataset: uspto-grants-2009_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07625895B2

Reaction notes

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