2-Amino-N-phenylbenzamide → 2-[(2,5-Dichloro-4-pyrimidinyl)amino]-N-phenylbenzamide

HRID 1864045Notes

Reaction equation

HRID 1864045 reaction equation
[NH2:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[C:4]([NH:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)=[O:5].[Cl:17][C:18]1[N:23]=[C:22](Cl)[C:21]([Cl:25])=[CH:20][N:19]=1>>[Cl:17][C:18]1[N:23]=[C:22]([NH:1][C:2]2[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=2[C:4]([NH:6][C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[O:5])[C:21]([Cl:25])=[CH:20][N:19]=1

Participants

3

Reactant 2

HCID 781422-Amino-N-phenylbenzamideHCID 2372592,4,5-Trichloropyrimidine

Product 1

HCID 579741332-[(2,5-Dichloro-4-pyrimidinyl)amino]-N-phenylbenzamide

Procedure

2-[(2,5-Dichloro-4-pyrimidinyl)amino]-N-phenylbenzamide was prepared from 2-amino-N-phenylbenzamide and 2,4,5-trichloropyrimidine using a procedure substantially as described for the preparation of Intermediate 1. Mass (M+H)+=358, 360.

Sources & evidence

ORD record
ord-5f8449f0af6b482baa4d2a72bc99559a
Source dataset
uspto-grants-2009_12
Patent number
US07625903B2

Reaction notes

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