3-azetidinecarboxylic Acid → 1-((3-Fluoro-4-(5-(1-phenylcyclopropyl)[1,3]thiazolo[5,4-b]pyridin-2-yl)phenyl)carbonyl)-3-azetidinecarboxylic acid

HRID 186419Notes

Reaction equation

HRID 186419 reaction equation
[F:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[OH:7])[cH:8][cH:9][c:10]1-[c:11]1[s:12][c:13]2[n:14][c:15]([C:20]3([c:23]4[cH:24][cH:25][cH:26][cH:27][cH:28]4)[CH2:21][CH2:22]3)[cH:16][cH:17][c:18]2[n:19]1.[NH:29]1[CH2:30][CH:31]([C:33](=[O:34])[OH:35])[CH2:32]1>>[F:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[N:29]2[CH2:30][CH:31]([C:33](=[O:34])[OH:35])[CH2:32]2)[cH:8][cH:9][c:10]1-[c:11]1[s:12][c:13]2[n:14][c:15]([C:20]3([c:23]4[cH:24][cH:25][cH:26][cH:27][cH:28]4)[CH2:21][CH2:22]3)[cH:16][cH:17][c:18]2[n:19]1

Participants

3

Reactant 2

HCID 931923-azetidinecarboxylic AcidHCID 573944063-Fluoro-4-(5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridin-2-yl)benzoic acid

Product 1

HCID 591748641-((3-Fluoro-4-(5-(1-phenylcyclopropyl)[1,3]thiazolo[5,4-b]pyridin-2-yl)phenyl)carbonyl)-3-azetidinecarboxylic acid

Sources & evidence

ORD record
ord-f3c43f471af842f9b528f1b6ff46774c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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