4-(2-Methoxyphenyl)piperidine → HCID 25027930, compound

HRID 1864372Notes

Reaction equation

HRID 1864372 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([S:9]([N:12]2[CH2:16][CH:15]([C:17](O)=[O:18])[N:14]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[C:13]2=[O:26])(=[O:11])=[O:10])[CH:6]=[CH:7][CH:8]=1.[CH3:27][O:28][C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=1[CH:35]1[CH2:40][CH2:39][NH:38][CH2:37][CH2:36]1>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([S:9]([N:12]2[CH2:16][CH:15]([C:17]([N:38]3[CH2:39][CH2:40][CH:35]([C:30]4[CH:31]=[CH:32][CH:33]=[CH:34][C:29]=4[O:28][CH3:27])[CH2:36][CH2:37]3)=[O:18])[N:14]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[C:13]2=[O:26])(=[O:10])=[O:11])[CH:6]=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 5447384-(2-Methoxyphenyl)piperidineHCID 67141122(RS)-1-(3-methoxy-benzenesulfonyl)-2-oxo-3-phenyl-imidazolidine-4-carboxylic acid

Product 1

HCID 25027930HCID 25027930, compound

Procedure

In analogy to example 1, (RS)-1-(3-methoxy-benzenesulfonyl)-2-oxo-3-phenyl-imidazolidine-4-carboxylic acid (step 4 of example 1) was reacted with 4-(2-methoxyphenyl)piperidine to give the title compound as a colorless solid. MS: 550.0 ([M+H]t)

Sources & evidence

ORD record
ord-d41b5514ccf042aea2573ff5b97ecdde
Source dataset
uspto-grants-2009_12
Patent number
US07625902B2

Reaction notes

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