Sodium Iodide → (RS)-1-Benzenesulfonyl-4-[4-(2,5-dimethyl-phenyl)-piperazine-1-carbonyl]-3-isopropyl-imidazolidin-2-one

Participants

Role	Name	HCID	Charge
Reactant	Sodium Iodide	HCID 5238	—
Reactant	Isopropyl isocyanate	HCID 61277	—
Reactant	((R)-1-benzenesulfonyl-aziridin-2-yl)-[4-(2,5-dimethyl-phenyl)-piperazin-1-yl]-methanone	HCID 86623480	—
Product	(RS)-1-Benzenesulfonyl-4-[4-(2,5-dimethyl-phenyl)-piperazine-1-carbonyl]-3-isopropyl-imidazolidin-2-one	HCID 25028147	—

Reaction Steps

In analogy to example 2, (RS)-(1-benzenesulfonyl-aziridin-2-yl)-[4-(2,5-dimethyl-phenyl)-piperazin-1-yl]-methanone (example 2, step 3) was reacted with sodium iodide and isopropyl isocyanate to give the title compound as a colorless solid. MS: 485.2 ([M+H]+)

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07625902B2
Source dataset	uspto-grants-2009_12
ORD ID	ord-7a45a06095f2495c94497dba660a4aea
Source note	uspto-grants-2009_12