HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Iodide → (RS)-1-Benzenesulfonyl-3-cyclopentyl-4-[4-(2,5-dimethyl-phenyl)-piperazine-1-carbonyl]-imidazolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | Cyclopentyl Isocyanate | HCID 643500 | — |
| Reactant | ((R)-1-benzenesulfonyl-aziridin-2-yl)-[4-(2,5-dimethyl-phenyl)-piperazin-1-yl]-methanone | HCID 86623480 | — |
| Product | (RS)-1-Benzenesulfonyl-3-cyclopentyl-4-[4-(2,5-dimethyl-phenyl)-piperazine-1-carbonyl]-imidazolidin-2-one | HCID 25028368 | — |
Reaction Steps
In analogy to example 2, (RS)-(1-benzenesulfonyl-aziridin-2-yl)-[4-(2,5-dimethyl-phenyl)-piperazin-1-yl]-methanone (example 2, step 3) was reacted with sodium iodide and cyclopentyl isocyanate to give the title compound as a colorless solid. MS: 511.1 ([M+H]+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07625902B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-c552092d33194b778c1fa190100f026e |
| Source note | uspto-grants-2009_12 |