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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1864395Generated: November 3, 2026

Triphenylphosphine → HCID 178425108, compound

https://huagongshe.com/reaction/1864395

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriphenylphosphineHCID 11776—
ReactantDiethyl azodicarboxylateHCID 5462977—
ReactantHCID 67141839HCID 67141839—
ProductHCID 178425108HCID 178425108—

Reaction Steps

In analogy to example 2, N-{(R)-2-[4-(2,5-dimethyl-phenyl)-piperazin-1-yl]-1-hydroxymethyl-2-oxo-ethyl}-benzenesulfonamide was reacted with triphenylphosphine and diethylazodicarboxylate to give ((R)-1-benzenesulfonyl-aziridin-2-yl)-[4-(2,5-dimethyl-phenyl)-piperazin-1-yl]-methanone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07625902B2
Source datasetuspto-grants-2009_12
ORD IDord-d0790a56b0324bd28293080fe30918cc
Source noteuspto-grants-2009_12