Benzenesulfonyl chloride → 2-Benzenesulfonylamino-3-hydroxy-propionic acid methyl ester

HRID 1864412Notes

Reaction equation

[CH3:1][O:2][C:3]([CH:5]([NH2:8])[CH2:6][OH:7])=[O:4].Cl.[C:10]1([S:16](Cl)(=[O:18])=[O:17])[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[CH3:1][O:2][C:3](=[O:4])[CH:5]([NH:8][S:16]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)(=[O:18])=[O:17])[CH2:6][OH:7]

Participants

Reactant 2

HCID 7369Benzenesulfonyl chloride

HCID 517373Methyl DL-serinate hydrochloride

Product 1

HCID 105632142-Benzenesulfonylamino-3-hydroxy-propionic acid methyl ester

Procedure

In analogy to example 1, DL-serinemethylester hydrochloride was reacted with benzenesulfonyl chloride to give 2-benzenesulfonylamino-3-hydroxy-propionic acid methyl ester.

Sources & evidence

ORD record: ord-bff1c645e81e427890bde9b263e457d8
Source dataset: uspto-grants-2009_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07625902B2

Reaction notes

Loading…