HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[3-(Trifluoromethyl)pyridin-2-yl]piperazine → (RS)-1-Benzenesulfonyl-3-cyclohexyl-4-[4-(3-trifluoromethyl-pyridin-2-yl)-piperazine-1-carbonyl]-imidazolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[3-(Trifluoromethyl)pyridin-2-yl]piperazine | HCID 2777786 | — |
| Reactant | (RS)-1-benzenesulfonyl-3-cyclohexyl-2-oxo-imidazolidine-4-carboxylic acid | HCID 67141201 | — |
| Product | (RS)-1-Benzenesulfonyl-3-cyclohexyl-4-[4-(3-trifluoromethyl-pyridin-2-yl)-piperazine-1-carbonyl]-imidazolidin-2-one | HCID 25029291 | — |
Reaction Steps
In analogy to example 1, (RS)-1-benzenesulfonyl-3-cyclohexyl-2-oxo-imidazolidine-4-carboxylic acid was coupled with 1-[3-(trifluoromethyl)pyrid-2-yl]piperazine to give the title compound as a colorless solid. MS: 565.8 ([M+H]+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07625902B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-a25891797bec459e92bfeddb0cf05072 |
| Source note | uspto-grants-2009_12 |