Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1864432Generated: October 31, 2026

Sodium hydride → HCID 25030008, compound

https://huagongshe.com/reaction/1864432

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium hydrideHCID 24758—
Reactant2-Fluorobenzenesulphonyl chlorideHCID 137761—
Reactant(RS)-5-[4-(2,5-dimethyl-phenyl)-piperazine-1-carbonyl]-1-phenyl-imidazolidin-2-oneHCID 67142096—
ProductHCID 25030008HCID 25030008—

Reaction Steps

In analogy to example 33, (RS)-5-[4-(2,5-dimethyl-phenyl)-piperazine-1-carbonyl]-1-phenyl-imidazolidin-2-one (example 33, step 1) was reacted with sodium hydride and 2-fluorobenzenesulfonyl chloride to give the title compound as a colorless solid. MS: 537.0 ([M+H]+)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07625902B2
Source datasetuspto-grants-2009_12
ORD IDord-38d0fc34a60749db8d6397843d5dbc6c
Source noteuspto-grants-2009_12