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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1864433Generated: October 31, 2026

Sodium hydride → HCID 25030009, compound

https://huagongshe.com/reaction/1864433

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium hydrideHCID 24758—
Reactant3-Fluorobenzenesulfonyl ChlorideHCID 2734258—
Reactant(RS)-5-[4-(2,5-dimethyl-phenyl)-piperazine-1-carbonyl]-1-phenyl-imidazolidin-2-oneHCID 67142096—
ProductHCID 25030009HCID 25030009—

Reaction Steps

In analogy to example 33, (RS)-5-[4-(2,5-dimethyl-phenyl)-piperazine-1-carbonyl]-1-phenyl-imidazolidin-2-one (example 33, step 1) was reacted with sodium hydride and 3-fluorobenzenesulfonyl chloride to give the title compound as a colorless solid. MS: 537.0 ([M+H]+)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07625902B2
Source datasetuspto-grants-2009_12
ORD IDord-62c2db73cb044b63a70e79a9420be994
Source noteuspto-grants-2009_12