2,5-Dimethyl-3-piperazin-1-ylpyrazine → HCID 25030245, compound

HRID 1864437Notes

Reaction equation

HRID 1864437 reaction equation
[C:1]1([S:7]([N:10]2[CH2:14][CH:13]([C:15](O)=[O:16])[N:12]([CH:18]3[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]3)[C:11]2=[O:24])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:25][C:26]1[C:27]([N:33]2[CH2:38][CH2:37][NH:36][CH2:35][CH2:34]2)=[N:28][C:29]([CH3:32])=[CH:30][N:31]=1>>[C:1]1([S:7]([N:10]2[CH2:14][CH:13]([C:15]([N:36]3[CH2:37][CH2:38][N:33]([C:27]4[C:26]([CH3:25])=[N:31][CH:30]=[C:29]([CH3:32])[N:28]=4)[CH2:34][CH2:35]3)=[O:16])[N:12]([CH:18]3[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]3)[C:11]2=[O:24])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 38119102,5-Dimethyl-3-piperazin-1-ylpyrazineHCID 67141201HCID 67141201, compound

Product 1

HCID 25030245HCID 25030245, compound

Procedure

In analogy to example 1, (RS)-1-benzenesulfonyl-3-cyclohexyl-2-oxo-imidazolidine-4-carboxylic acid (example 39, step 4) was coupled with 3′,6′-dimethyl-3,4,5,6-tetrahydro-2H-[1,2′]bipyrazinyl (CAS 59215-42-8) to give the title compound as a colorless solid. MS: 526.8 ([M+H]+)

Sources & evidence

ORD record
ord-8fc9c96233084776a7a7babb9846e827
Source dataset
uspto-grants-2009_12
Patent number
US07625902B2

Reaction notes

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