HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-Chloropyridin-2-yl)piperazine hydrochloride → (RS)-1-Benzenesulfonyl-3-(2-chloro-phenyl)-4-[4-(3-chloro-pyridin-2-yl)-piperazine-1-carbonyl]-imidazolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-Chloropyridin-2-yl)piperazine hydrochloride | HCID 20455074 | — |
| Reactant | HCID 67140727 | HCID 67140727 | — |
| Product | (RS)-1-Benzenesulfonyl-3-(2-chloro-phenyl)-4-[4-(3-chloro-pyridin-2-yl)-piperazine-1-carbonyl]-imidazolidin-2-one | HCID 25030246 | — |
Reaction Steps
In analogy to example 1, (RS)-1-benzenesulfonyl-3-(2-chloro-phenyl)-2-oxo-imidazolidine-4-carboxylic acid (example 49, step 2) was coupled with 1-(3-chloro-pyridin-2-yl)-piperazine hydrochloride (CAS 85386-86-3) to give the title compound as a colorless solid. MS: 560.2 ([M+H]+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07625902B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-6ef6371ed3ec40cdbe9d0bcff7446bf8 |
| Source note | uspto-grants-2009_12 |