HRID1864462

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID3811910

2,5-dimethyl-3-piperazin-1-ylpyrazine

C10H16N4

结构：O=C(O)C1CN(S(=O)(=O)c2ccccc2)C(=O)N1c1ccccc1Cl

HCID67140727

未命名化合物

PRODUCTS

生成物

结构：Cc1cnc(C)c(N2CCN(C(=O)C3CN(S(=O)(=O)c4ccccc4)C(=O)N3c3ccccc3Cl)CC2)n1

HCID25027495

未命名化合物

PROCEDURE

实验过程

In analogy to example 1,1-benzenesulfonyl-3-(2-chloro-phenyl)-2-oxo-imidazolidine-4-carboxylic acid (example 49, step 2) was coupled with 3′,6′-dimethyl-3,4,5,6-tetrahydro-2H-[1,2′]bipyrazinyl (CAS [59215-42-8]) to give the title compound as a colorless solid. MS: 555.2 ([M+H]+)

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-5c0a1c55711c41578788321f85ecb5cd
来源数据集: uspto-grants-2009_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07625902B2
来源说明: uspto-grants-2009_12

反应 SMILES

[C:1]1([S:7]([N:10]2[CH2:14][CH:13]([C:15]([OH:17])=O)[N:12]([C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=3[Cl:24])[C:11]2=[O:25])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:26][C:27]1[C:28]([N:34]2[CH2:39][CH2:38][NH:37][CH2:36][CH2:35]2)=[N:29][C:30]([CH3:33])=[CH:31][N:32]=1>>[C:1]1([S:7]([N:10]2[CH2:14][CH:13]([C:15]([N:37]3[CH2:38][CH2:39][N:34]([C:28]4[C:27]([CH3:26])=[N:32][CH:31]=[C:30]([CH3:33])[N:29]=4)[CH2:35][CH2:36]3)=[O:17])[N:12]([C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=3[Cl:24])[C:11]2=[O:25])(=[O:9])=[O:8])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1