1-(2,5-Xylyl)piperazine → HCID 25027713, compound

HRID 1864470Notes

Reaction equation

HRID 1864470 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[CH:12]([C:13](O)=[O:14])[CH2:11][N:10]([S:16]([CH:19]([CH3:21])[CH3:20])(=[O:18])=[O:17])[C:9]1=[O:22].[CH3:23][C:24]1[CH:29]=[CH:28][C:27]([CH3:30])=[CH:26][C:25]=1[N:31]1[CH2:36][CH2:35][NH:34][CH2:33][CH2:32]1>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[CH:12]([C:13]([N:34]2[CH2:35][CH2:36][N:31]([C:25]3[CH:26]=[C:27]([CH3:30])[CH:28]=[CH:29][C:24]=3[CH3:23])[CH2:32][CH2:33]2)=[O:14])[CH2:11][N:10]([S:16]([CH:19]([CH3:20])[CH3:21])(=[O:17])=[O:18])[C:9]1=[O:22]

Participants

3

Reactant 2

HCID 705421-(2,5-Xylyl)piperazineHCID 67141525HCID 67141525, compound

Product 1

HCID 25027713HCID 25027713, compound

Procedure

In analogy to example 1, (RS)-3-(2-chloro-phenyl)-2-oxo-1-(propane-2-sulfonyl)-imidazolidine-4-carboxylic acid was coupled with 1-(2,5-dimethylphenyl)piperazine to give the title compound as a colorless solid. MS: 519.3 ([M+H]+)

Sources & evidence

ORD record
ord-f5a90b166dd141bdabdc6ca429a1d36f
Source dataset
uspto-grants-2009_12
Patent number
US07625902B2

Reaction notes

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