HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → Quinoline-3-carbonyl Chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Quinoline-3-carboxylic acid | HCID 80971 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | Quinoline-3-carbonyl Chloride | HCID 11030631 | 90% |
Reaction Steps
10 g of 3-quinoline carboxylic acid was mixed with 8.5 ml of thionyl chloride and 150 ml of toluene, and allowed to react at 100° C. for 12 hours. The reaction mixture was condensed under a reduced pressure, to obtain a residue that gave 10 g of the title compound (yield 90%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07625926B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-25eb61c9cda34c0e96a8f82c5a06e001 |
| Source note | uspto-grants-2009_12 |