HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HM-30181 hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | N-[2-[2-[4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-2H-tetrazol-5-yl]-4,5-dimethoxyphenyl]-4-oxo-4H-1-benzopyran-2-carboxamide | HCID 11399764 | — |
| Product | HM-30181 hydrochloride | HCID 86278312 | 89% |
Reaction Steps
The procedure of Example 33 was repeated except for using 1.5 g of the compound obtained in Example 21 and 0.1 ml of hydrochloric acid as starting materials to obtain 1.4 g of the title compound (yield 89%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07625926B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-cbd9426eabe2455e88bca7f6c5b4b625 |
| Source note | uspto-grants-2009_12 |