Ethyl Acetate → HCID 178430167, compound

Participants

Reaction Steps

To a solution of compound 2D (11.0 mg, 0.0250 mmol) in THF (1 mL) at 0° C. was added a 1.0 M TBAF solution in THF (0.250 mL, 0.250 mmol). After stirring at rt for 1 h, saturated aqueous NH4Cl and EtOAc were added. The layers were separated, and the organic layer was washed with brine, then dried over MgSO4, filtered and concentrated. Purification via flash chromatography (silica gel, 0-85% EtOAc in hexane) provided the title compound (4.6 mg). LCMS: m/z 292 [M+H]+.

Provenance & Evidence