HCID 178430161, compound → HCID 178430159, compound

HRID 1864698Notes

Reaction equation

HRID 1864698 reaction equation
[Si]([O:8][C@@H:9]1[C@:16]2([CH3:17])[N:12](/[C:13](=[N:18]/[C:19]3[CH:26]=[CH:25][C:22]([C:23]#[N:24])=[C:21]([Cl:27])[C:20]=3[CH3:28])/[O:14][CH2:15]2)[CH2:11][CH2:10]1)(C(C)(C)C)(C)C.O[C@H]1[C@@H]2N(/C(=N/C3C=CC(C#N)=C(Cl)C=3C)/OC2)CC1>>[OH:8][C@@H:9]1[C@:16]2([CH3:17])[N:12](/[C:13](=[N:18]/[C:19]3[CH:26]=[CH:25][C:22]([C:23]#[N:24])=[C:21]([Cl:27])[C:20]=3[CH3:28])/[O:14][CH2:15]2)[CH2:11][CH2:10]1

Participants

3

Reactant 2

HCID 178430161HCID 178430161, compoundHCID 178430168HCID 178430168, compound

Product 1

HCID 178430159HCID 178430159, compound

Procedure

The title compound was prepared from compound 4E following the procedure found in Example 1 for the preparation of compound 1J. LCMS: m/z 306 [M+H]+.

Sources & evidence

ORD record
ord-d9d4ce7c584c4b62818504644b2f0a21
Source dataset
uspto-grants-2009_12
Patent number
US07625923B2

Reaction notes

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