HCID 178430168, compound → HCID 178430191, compound

HRID 1864708Notes

Reaction equation

HRID 1864708 reaction equation
[Si]([O:8][C@H:9]1[C@H:16]2[N:12](/[C:13](=[N:21]/[C:22]3[CH:29]=[CH:28][C:25]([C:26]#[N:27])=[C:24]([Cl:30])[C:23]=3[CH3:31])/[O:14][C@H:15]2[C:17]([F:20])([F:19])[F:18])[CH2:11][CH2:10]1)(C(C)(C)C)(C)C.O[C@H]1[C@@H]2N(/C(=N/C3C=CC(C#N)=C(Cl)C=3C)/OC2)CC1>>[OH:8][C@H:9]1[C@@H:16]2[N:12](/[C:13](=[N:21]/[C:22]3[CH:29]=[CH:28][C:25]([C:26]#[N:27])=[C:24]([Cl:30])[C:23]=3[CH3:31])/[O:14][C@H:15]2[C:17]([F:18])([F:20])[F:19])[CH2:11][CH2:10]1

Participants

3

Reactant 2

HCID 178430168HCID 178430168, compoundHCID 178430194HCID 178430194, compound

Product 1

HCID 178430191HCID 178430191, compound

Procedure

The title compound was prepared from compound 8A following a procedure analogous to that found in Example 1 in the preparation of compound 1J. MS: m/z 360 [M+H]+

Sources & evidence

ORD record
ord-c5d20fc38daf401e800fa4cba8d1aa01
Source dataset
uspto-grants-2009_12
Patent number
US07625923B2

Reaction notes

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