Triacetoxyperiodinane → HCID 86622382, compound

Participants

Reaction Steps

To a solution of 180 mg (0.429 mmol) 3-5 in 2.0 mL DCM at RT under N2 was added 218 mg (0.515 mmol) Dess-Martin Periodinane. After stirring for 30 min, the reaction was quenched by slowly adding saturated aqueous Na2SO3 solution followed by saturated aqueous NaHCO3 solution. The mixture stirred for 15 min before it was poured into EtOAc and separated. The organic phase was washed with 1:1 saturated aqueous Na2SO3-saturated aqueous NaHCO3 solution, water, brine, then dried with Na2SO4 and concentrated to yield 3-6 as a white foam.

Provenance & Evidence