HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 40531003, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 66972967 | HCID 66972967 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 40531003 | HCID 40531003 | — |
Reaction Steps
To a solution of tert-butyl (2S,5R)-2-methyl-3-oxo-5-phenylmorpholine-4-carboxylate from Step D (160 mg, 0.55 mmol) in CH2Cl2 (2 mL) at ambient temperature was added TFA (0.41 mL, 5.5 mmol). After stirring for 1 h, the reaction mixture was concentrated in vacuo to give the title compound. MS: m/z=192 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07625901B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-140482ec1da84158a40b2cffae5de27a |
| Source note | uspto-grants-2009_12 |