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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1864837Generated: October 31, 2026

Trifluoroacetic acid → HCID 40531003, compound

https://huagongshe.com/reaction/1864837

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 66972967HCID 66972967—
SolventDichloromethaneHCID 6344—
ProductHCID 40531003HCID 40531003—

Reaction Steps

To a solution of tert-butyl (2S,5R)-2-methyl-3-oxo-5-phenylmorpholine-4-carboxylate from Step D (160 mg, 0.55 mmol) in CH2Cl2 (2 mL) at ambient temperature was added TFA (0.41 mL, 5.5 mmol). After stirring for 1 h, the reaction mixture was concentrated in vacuo to give the title compound. MS: m/z=192 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07625901B2
Source datasetuspto-grants-2009_12
ORD IDord-140482ec1da84158a40b2cffae5de27a
Source noteuspto-grants-2009_12