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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1864976Generated: October 25, 2026

Dibenzyl malonate → 3-Ethoxycarbonyl-4-nitrophenylmalonic acid dibenzyl ester

https://huagongshe.com/reaction/1864976

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDibenzyl malonateHCID 84754—
ReactantEthyl 5-chloro-2-nitrobenzoateHCID 603450—
Product3-Ethoxycarbonyl-4-nitrophenylmalonic acid dibenzyl esterHCID 57683244—

Reaction Steps

The 5-chloro-2-nitrobenzoic acid ethyl ester (4.40 g) obtained in Example 9-4b) and malonic acid dibenzyl ester were subjected to reactions similar to those in Example 1-3a) to give the title compound (4.61 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07625948B2
Source datasetuspto-grants-2009_12
ORD IDord-4165df21537a43e38a8f148ea4b6f6fa
Source noteuspto-grants-2009_12