Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-Bromoadamantane | HCID 79106 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 1-PHENYLADAMANTANE | HCID 522696 | — |
Reaction Steps
Add 1-bromoadamantane (10 g, 46.5 mmols), potassium carbonate (7.7 g, 55.8 mmols) and palladium on carbon (250 mg, catalytic) in benzene and heat to 120° C. for 1 week. Cool the reaction to room temperature and filter over Celite® rinsing with EtOAc. Concentrate under reduce pressure to provide the title compound. 1H NMR (400 MHz; CDCl3) δ 7.2-7.4(m, 5H), 2.10(s, 3H), 1.92(s, 6H), 1.77(s, 6H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07625932B2 |
|---|
| Source dataset | uspto-grants-2009_12 |
|---|
| ORD ID | ord-165b889c4f324f28bb14ef21e29eab12 |
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| Source note | uspto-grants-2009_12 |
|---|
