Malononitrile → 2-(1-Ethoxypropylidene)malononitrile

HRID 1865046Notes

Reaction equation

HRID 1865046 reaction equation
[C:1](#[N:5])[CH2:2][C:3]#[N:4].[CH2:6]([O:8][C:9](OCC)(OCC)[CH2:10][CH3:11])[CH3:7]>>[CH2:6]([O:8][C:9](=[C:2]([C:1]#[N:5])[C:3]#[N:4])[CH2:10][CH3:11])[CH3:7]

Participants

3

Reactant 2

HCID 8010MalononitrileHCID 66995Ethyl orthopropionate

Product 1

HCID 2314702-(1-Ethoxypropylidene)malononitrile

Procedure

Add malononitrile (200.00 g, 3.03 mol) and triethylorthopropionate (61.00 mL, 3.03 mol) and heat to reflux with stirring. After 3 hours, cool the reaction to room temperature. After 18 hours, purify by vacuum distillation to afford the title compound.

Workup

  1. temperatureheat
  2. temperatureto reflux
  3. temperaturecool
  4. customthe reaction to room temperature
  5. waitAfter 18 hours
  6. distillationpurify by vacuum distillation

Sources & evidence

ORD record
ord-52864ddcb4184022939ac12fcb0fe581
Source dataset
uspto-grants-2009_12
Patent number
US07625932B2

Reaction notes

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