4-Formylphenylboronic Acid → 2-(4-Formylphenyl)thiophene-3-carbonitrile

HRID 1865129Notes

Reaction equation

HRID 1865129 reaction equation
I[C:2]1[S:3][CH:4]=[CH:5][C:6]=1[C:7]#[N:8].[CH:9]([C:11]1[CH:16]=[CH:15][C:14](B(O)O)=[CH:13][CH:12]=1)=[O:10]>>[CH:9]([C:11]1[CH:16]=[CH:15][C:14]([C:2]2[S:3][CH:4]=[CH:5][C:6]=2[C:7]#[N:8])=[CH:13][CH:12]=1)=[O:10]

Participants

3

Reactant 2

HCID 5910734-Formylphenylboronic AcidHCID 109773992-Iodothiophene-3-carbonitrile

Product 1

HCID 579749902-(4-Formylphenyl)thiophene-3-carbonitrile

Procedure

In a manner analogous to the procedure set forth in example A-239, the title compound is prepared from 2-iodo-3-cyano-thiophene and 4-formylphenyl boronic acid.

Sources & evidence

ORD record
ord-5db34e4a734a4134ab5990c1c9ba1693
Source dataset
uspto-grants-2009_12
Patent number
US07625932B2

Reaction notes

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